TY - JOUR KW - Dapsone KW - Immunosuppression KW - leprosy KW - Leprosy reactions KW - PJP prophylaxis AU - Ramírez-Perea N AU - Moran-Castaño C AU - Perez-Molina J AB -

Leprosy reactions often require prolonged high-dose steroids or immunosuppressive drugs, putting patients at risk of Pneumocystis jirovecii pneumonia (PJP). However, no PJP cases are reported, possibly due to dapsone treatment for leprosy. In patients with leprosy reactions not receiving dapsone because of toxicity or resistance and requiring long-term immunosuppression, PJP prophylaxis should be considered.

BT - Pneumonia (Nathan Qld.) C1 -

https://www.ncbi.nlm.nih.gov/pubmed/38576014

DA - 04/2024 DO - 10.1186/s41479-024-00127-x IS - 1 J2 - Pneumonia (Nathan) LA - eng N2 -

Leprosy reactions often require prolonged high-dose steroids or immunosuppressive drugs, putting patients at risk of Pneumocystis jirovecii pneumonia (PJP). However, no PJP cases are reported, possibly due to dapsone treatment for leprosy. In patients with leprosy reactions not receiving dapsone because of toxicity or resistance and requiring long-term immunosuppression, PJP prophylaxis should be considered.

PY - 2024 SP - 1 EP - 3 T2 - Pneumonia (Nathan Qld.) TI - Should prophylaxis against Pneumocystis jirovecii pneumonia be considered in selected patients with leprosy reactions? UR - https://pneumonia.biomedcentral.com/counter/pdf/10.1186/s41479-024-00127-x.pdf VL - 16 SN - 2200-6133 ER -